First appearance: Amazing Spider-Man: Renew Your Vows #1

What if Brand New Day never happened? That was the question when Marvel decided to launch this universe as part of their Secret War series. In this universe, there are a few differences (including Jean and Wolverine being married) but the main one was that Spider-man and MJ didn’t make a deal with Mephisto to save Aunt May. They remained married and had another daughter, Anna-May, who would go on to become her own Spider-hero, Spiderling or later the Patternmaker.